Montefiore Medical Center

This study tests whether offering buprenorphine treatment directly at syringe service programs (SSPs) helps more people start and stay on medication for opioid use disorder compared to referring them elsewhere. About 512 adults who use SSPs and have moderate to severe opioid use …

This study tests whether a single injection of dexamethasone works as well as a 5-day course of prednisone pills to prevent asthma patients from returning to the emergency room. About 182 adults with asthma will be randomly assigned to get either the shot or the pills. Researcher…

This study tests whether adding two FDA-approved cannabinoids—dronabinol (synthetic THC) and epidiolex (CBD)—to standard buprenorphine treatment can help people with opioid use disorder stay in treatment and reduce opioid use. The trial will enroll 40 adults who recently started …

This phase 2 trial tests two different immunotherapy drug combinations (durvalumab with monalizumab or oleclumab) followed by personalized radiation for people with advanced non-small cell lung cancer that has a high PD-L1 score. The goal is to see which combination works better …

This study will compare two nausea medications, fosaprepitant and metoclopramide, in 212 adults who come to the emergency department with nausea or vomiting. The goal is to see which drug provides faster and more lasting relief with fewer side effects. Fosaprepitant is a newer dr…

This study tests a mobile app designed to help Black and Hispanic adults with inflammatory bowel disease (IBD) manage stress and improve their quality of life. The app teaches coping skills, mindfulness, and disease acceptance. Researchers want to see if the app is practical and …

This study tests two intravenous medications—metoclopramide and acetaminophen—to see which one better relieves acute concussion symptoms like headache, dizziness, and nausea in emergency room patients. Researchers will enroll 200 adults with mild head injuries and track their sym…

This trial tests whether people with mild diverticulitis can be safely treated at home with just pain medicines (ibuprofen and acetaminophen) instead of antibiotics. 556 participants will be randomly assigned to receive either pain medicines alone or pain medicines plus an antibi…

This study compares intravenous (IV) acetaminophen to oral acetaminophen for treating acute pelvic pain in the emergency department. About 140 women with pelvic pain and a pain score of 4 or higher will be randomly assigned to receive either IV or oral acetaminophen, plus a dummy…

This study will test whether a mobile app called RestoreMe can help cancer patients get personalized nutrition and activity advice. Researchers plan to enroll 150 adults who are about to start, are currently receiving, or have completed cancer treatment. Participants will use the…

This study will compare new, single-use coblator wands with reprocessed (cleaned and reused) wands in 30 children having tonsil or adenoid surgery. The main goal is to see if surgeons are just as comfortable using the reprocessed wands. The study also looks at technical issues an…

This study looks at whether making a bladder flap during a first C-section affects the formation of a scar defect (niche) in the uterus. Researchers will compare women who get a bladder flap to those who don't, using an ultrasound 6-8 weeks after delivery. The goal is to see if s…