Jiangsu Hengrui Medicine Co., Ltd.

This study tested a new medicine called HR091506 for adults with gout and high uric acid. It compared the drug to another common treatment, febuxostat. The main goal was to see if HR091506 could safely lower uric acid levels below a target at 28 weeks. A total of 765 adults aged …

This study tested an experimental drug called HR19042 in 316 adults with IgA nephropathy, a kidney disease. The goal was to see if the drug could reduce protein in the urine and protect kidney function compared to a placebo. The trial is now complete, and results will help determ…

This study tested a combination of an immunotherapy drug (SHR-1210) with either a targeted therapy (apatinib) or chemotherapy in 157 people with advanced liver or bile duct cancer. The goal was to see if the combinations are safe and can shrink tumors. Participants either had fai…

This study tested a combination of two drugs, SHR-1210 (an immunotherapy) and apatinib (a targeted therapy), in 190 adults with advanced liver cancer that did not respond to or could not tolerate prior treatment. The goal was to see if the combination could shrink tumors and cont…

This study tested whether an oral tablet (SHR7280) works as well as a daily injection (ganirelix) for preventing early ovulation in women undergoing IVF. About 317 women aged 20-39 with infertility took part. The goal was to see if the pill could offer a more convenient option wi…

This study tested whether adding rivoceranib to camrelizumab after surgery or ablation helps prevent liver cancer from returning in patients at high risk. About 251 participants received either the combination or camrelizumab alone. The main goal was to see how long patients stay…

This early-phase study tested an experimental cancer pill, HRS7415, in 38 adults with advanced solid tumors that had spread. The main goals were to check the drug's safety, find the best dose, and see how the body processes it. Researchers monitored side effects and tumor respons…

This study tested a new targeted therapy pill, pyrotinib, against standard chemotherapy (docetaxel) in 151 people with advanced non-squamous lung cancer that has a specific HER2 gene change. All participants had already tried platinum-based chemo without success. The goal was to …

This study tested a new drug called HRS-9190 in 70 adults having planned surgery. The drug is meant to relax muscles so doctors can place a breathing tube more easily during anesthesia. Researchers compared it to a standard muscle relaxant to see if it works as well and is safe.

This early-phase study tested an experimental drug called SHR-A1811 in 101 people with advanced stomach or colorectal cancers that have a specific protein (HER2). The main goals were to find a safe dose and check for side effects. Researchers also looked for signs that the drug m…

This study tested a new medication called HRG2010 in 165 people with Parkinson's disease who experience motor fluctuations — times when their symptoms return between doses. The goal was to see if HRG2010 could reduce daily 'off' time better than a standard extended-release carbid…

This early-phase study tested a new drug called SHR-A1811 in 396 adults with advanced solid tumors that have a specific marker (HER2). The main goals were to check safety and find the right dose. Researchers also looked for signs that the drug might shrink or control tumors. This…

This phase 3 trial tested whether adding the immunotherapy drug camrelizumab to standard chemotherapy, followed by camrelizumab plus another drug (apatinib), helps people with advanced stomach or gastroesophageal junction cancer live longer. The study included 885 adults who had …

This study tested a new drug called HRS-9190 against a standard drug (rocuronium) to keep muscles relaxed during surgery. 103 adults having planned surgery took part. The main goal was to measure how quickly muscle function returns after the last dose. The study aims to see if HR…

This study tested a new medicine called HR17031 against a standard insulin (insulin glargine) in 401 Chinese adults with type 2 diabetes whose blood sugar was not well controlled with oral medications. The goal was to see if HR17031 could lower blood sugar levels (HbA1c) more eff…

This study tested a combination of two drugs, SHR-1210 and apatinib, in 210 people with advanced non-small cell lung cancer that had stopped responding to earlier treatments. The goal was to see if the combination was safe and could shrink tumors. Participants received the drugs …

This study tested a drug called remimazolam to see how well it works and how safe it is for sedating children and teenagers during surgery. About 249 young patients took part. The goal was to see if the drug could successfully start and maintain sedation while keeping side effect…

This study tested a sedative called remimazolam tosilate in 214 ICU patients who were on breathing machines. The goal was to see if it could safely keep patients at the right sedation level without needing extra rescue medication. The trial compared remimazolam to another active …

This study tested a drug called remimazolam tosilate to sedate ICU patients who need a breathing machine for three days or more. The goal was to see if the drug keeps patients at the right level of calm without needing extra sedatives. Twenty-four adults took part in this early-p…

This early-stage study tested a new drug called HR011408 in 62 healthy adults to see if it is safe and how the body processes it. The drug is being developed for diabetes, but this trial did not test if it works. Participants received single doses of two different versions of the…

This study looked at the safety of a sedative called remimazolam tosilate when used for general anesthesia and during a breathing tube procedure (bronchoscopy). Over 1,200 patients were observed in real-world medical settings in China. The main goal was to track any side effects …

This study tested how a new prostate cancer drug (SHR3680) affects the way the body processes three other common drugs: digoxin, rosuvastatin, and metformin. Thirty-six men with prostate cancer took part. The goal was to understand potential drug interactions, not to treat the ca…

This study looked at how a common antibiotic (rifampicin) changes the way the body processes an experimental prostate cancer drug (HRS-5041). Sixteen healthy men took HRS-5041 alone and then with rifampicin to see if the antibiotic alters drug levels. The goal was to gather safet…

This study looked at how a new injection called HRS-8427 changes the way the body processes two other drugs (bupropion and midazolam) in 14 healthy adults. The goal was to see if HRS-8427 affects liver enzymes that break down many medications. Results will help doctors understand…

This study looked at the safety of a sedative called remazolam in 2000 Chinese patients undergoing painless stomach or colon exams. Researchers tracked side effects and serious reactions to understand how the drug performs in everyday medical practice. The goal was to gather real…

This early-stage study tested the safety and how the body processes a new drug called HRS-9190 in 53 healthy adults aged 18 to 45. Participants received different doses to see how the drug behaves and if it causes side effects. The goal was to gather information for future resear…

This early-stage study tested a new drug called HRS-9190 in 49 healthy adults to see if it is safe and how the body processes it. The drug is designed to relax muscles, but this trial did not aim to treat any disease. Researchers measured side effects and drug levels in the blood…

This study looked at how a single dose of HR17031 moves through the body in people with mild, moderate, severe, or end-stage kidney disease compared to those with normal kidneys. A total of 24 adults with type 2 diabetes took part. The goal was to understand how kidney function a…

This study checked whether a new form of the painkiller bupivacaine (liposomal) is absorbed in the body the same way as the approved version. It involved 36 healthy adults aged 18-45. The goal was to measure drug levels in the blood, not to treat pain directly.

This early-stage study tested a single shot of a new drug called SHR-3167 in 24 healthy men, comparing it to standard insulin glargine. The goal was to see how the drug works in the body and check for safety issues. Since participants were healthy, the study was purely for gather…

This study looked at how two common drugs (ritonavir and itraconazole) change the way the body processes a new experimental drug called SHR-A1811 in people with advanced HER2-positive breast cancer. Seventeen participants received the drug alone and then with each of the other me…

This study looked at how a new drug called SHR7280 interacts with six common medications in 20 healthy men. The goal was to see if SHR7280 changes how these drugs are processed in the body. Results will help doctors use SHR7280 safely for conditions like endometriosis and uterine…