Italian Sarcoma Group

This study is testing whether the drug trabectedin can help control advanced mesenchymal chondrosarcoma, a rare and aggressive type of bone and soft tissue cancer. It is for patients aged 16 and older whose cancer has continued to grow despite prior chemotherapy. The main goal is…

This study aims to determine whether surgery or radiation therapy works better for controlling primary sacral chordoma, a rare type of bone tumor near the tailbone. The trial will enroll 100 adults with newly diagnosed tumors who haven't had previous treatment. Participants will …

This study is testing whether a combination of two chemotherapy drugs, lurbinectedin and irinotecan, can help control advanced desmoplastic small round cell tumor (DSRCT), a rare and aggressive cancer. It is for patients aged 15 and older whose cancer has spread and worsened afte…

This study compares two cancer drugs, trabectedin and gemcitabine, to see which works better for controlling advanced leiomyosarcoma after initial chemotherapy has stopped working. It will enroll 100 adults whose cancer has progressed despite previous treatment. The trial include…

This study aims to learn from the past to improve future care for a rare type of breast cancer called breast sarcoma. Researchers will look back at the medical records of about 300 patients treated between 2000 and 2020. By analyzing their treatments and outcomes, the goal is to …

This study aims to collect information to better understand endometrial stromal tumors, a rare type of cancer. Researchers will look at the medical records of about 100 patients who have been diagnosed with this condition. The goal is to learn more about how the disease behaves o…

This study aims to gather detailed information on patients with localized angiosarcoma, a rare and aggressive cancer. It will follow 250 patients across multiple Italian hospitals as they receive standard care. The goal is to better understand the disease's characteristics and ho…

This study aims to collect detailed information about how doctors currently treat Ewing sarcoma of bone in real-world settings. Researchers will follow 100 patients under age 50 to document their treatments, outcomes, and side effects. The goal is to gather knowledge that can hel…

This Italian study aims to learn more about epithelioid sarcoma, a rare type of cancer. Researchers will follow 100 patients to see what treatments they receive and how the disease progresses over time. The goal is to gather information that could help improve future care by unde…