Institut Bergonié

This study was planned to test two drugs, Ezabenlimab and BI 907828, in people with advanced solid tumors like sarcoma, lung cancer, and breast cancer. The goal was to see if the combination could control the disease for at least 24 weeks. However, the study was withdrawn before …

This study was planned to test a combination of chemotherapy drugs (cisplatin and docetaxel) with radiation therapy for people with advanced non-small cell lung cancer that could not be removed by surgery. The goal was to see if this approach was feasible and could shrink tumors.…

This study tests whether adding the immunotherapy drug retifanlimab to standard chemotherapy before surgery can improve outcomes for people with certain soft-tissue sarcomas. About 66 adults with grade 2 or 3 sarcomas will be randomly assigned to receive either chemo alone or che…

This study looks at whether a vaginal ultrasound-guided biopsy can accurately tell if a uterine tumor is cancerous (sarcoma) or benign (fibroid) before surgery. About 19 women with suspicious tumors will get the biopsy, and results will be checked against the final diagnosis afte…

This study tests whether using a special monitor (ANI) during ovarian cancer surgery to guide pain medicine can lower the chance of chronic pain three months after the operation. About 126 women having open surgery for ovarian cancer will be randomly assigned to standard care or …

This study tests a new care plan that uses technology to help doctors better manage the health of older adults (70+) who have cancer and other medical conditions. The goal is to see if this approach improves their quality of life after 6 months. About 720 people with breast, lung…

This study brings together cancer experts to agree on standard definitions for key measurements used in cancer clinical trials, such as how long patients live without their cancer getting worse. Currently, different trials define these measurements in different ways, making it ha…

This study follows up to 430 people with Cowden's disease and PTEN gene mutations to see how often they develop cancer. Researchers will track any cancer events, especially breast and thyroid cancers. The goal is to better understand cancer risks in this group to improve future s…

This study aimed to see if a focused ultrasound device could destroy breast tumors before mastectomy. The treatment was guided by MRI and done under local anesthesia. However, the study was withdrawn before any participants were enrolled, so no results are available.

This study checks for muscle loss (sarcopenia) in 25 women with advanced ovarian cancer who cannot have surgery right away. Researchers use CT scans to see how common muscle loss is before and during chemotherapy. The goal is to learn if muscle loss affects treatment timing and o…

This study looks at whether people over 65 with cancer can use an online tool to regularly report their symptoms and quality of life during treatment. The goal is to see if this approach is practical and helps doctors catch problems early. About 33 participants will fill out week…

This study aimed to measure certain proteins (chemokines) in the blood, urine, and tumors of people with prostate cancer to see how they change over time. It was designed for patients starting a new treatment, such as hormone therapy or chemotherapy. However, the study was withdr…

This study follows 25 people aged 70 and older who had surgery for soft tissue sarcoma in their leg. The goal is to see how the surgery changes their physical function and quality of life. Researchers use questionnaires to track recovery and identify factors that predict better o…