I.m. Sechenov First Moscow State Medical University

This trial compares two surgical methods for removing oral epithelial dysplasia, a precancerous condition of the mouth lining. One group receives laser surgery, while the other has traditional scalpel removal. Researchers measure wound healing speed, swelling, redness, and pain t…

This study tested whether using a smartphone app and phone calls to monitor patients after a heart failure hospital stay helps doctors safely increase their medications. 66 adults with chronic heart failure and low ejection fraction were split into two groups: one received usual …

This study tested two types of dental fillings for cavities and tooth wear at the gum line in 20 professional ballet dancers. One filling was a ceramic-like material (PICN) and the other was a self-hardening composite. Over 24 months, the ceramic fillings had zero failures, while…

This study tested two ways to thicken gum tissue around dental implants: using a collagen matrix or a small piece of the patient's own connective tissue. Fifty-two adults with thin gums received one of the two treatments. The researchers measured gum thickness, pain, swelling, an…

This study tested an artificial intelligence tool called RetinAIcheck to see if it can accurately detect and grade hypertensive retinopathy—eye damage caused by high blood pressure. Researchers used 729 patients' eye photos and compared the AI's results to assessments by eye doct…

This study tested a device called Reacor that uses biofeedback to teach mindfulness by showing your heart rate and brain waves in real time. 188 adults with anxiety disorders were split into three groups: biofeedback alone, the medication escitalopram alone, or both together. The…

This study tested whether colchicine, an anti-inflammatory drug, can lower inflammation in people with a specific type of heart failure called HFpEF. 42 adults with heart failure symptoms and signs of inflammation took part. The goal was to see if colchicine could reduce markers …

This study tested whether an internet-based cognitive-behavioral therapy program (iCBT-I) can help people with chronic insomnia. 107 adults were randomly assigned to receive the online program or usual care. The program included educational videos, sleep tracking, and techniques …

This completed study looked at 115 people with inflammatory bowel disease (IBD) to see if their condition raises the risk of atherosclerosis, a hardening of the arteries that can lead to heart attacks and strokes. Researchers measured artery stiffness and thickness, and tracked h…

This completed study measured oxygen and carbon dioxide levels in the throat of 14 healthy volunteers while they received oxygen through a nasal cannula, face mask, or standard non-rebreather mask. The goal was to understand how different delivery methods affect gas composition i…