Gum graft showdown: collagen vs. your own tissue for implants

NCT ID NCT05870774

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested two ways to thicken gum tissue around dental implants: using a collagen matrix or a small piece of the patient's own connective tissue. Fifty-two adults with thin gums received one of the two treatments. The researchers measured gum thickness, pain, swelling, and aesthetics over 6 months to see which method worked better.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
collagen matrix (Fibro-Gide) or connective tissue graft
What this could lead to
If successful, this could show that a collagen matrix is a good alternative to using a patient's own tissue for gum thickening around dental implants.
What could go wrong
This is a small, completed trial with only 52 participants, so results may not apply to everyone. The collagen matrix might not work as well as the natural graft.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • I.M. Sechenov First Moscow State Medical University

    Moscow, 119991, Russia

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