Hutchmed

This early-stage study is testing a new drug called HMPL-A580 in adults with advanced solid tumors that cannot be removed by surgery. The main goals are to find a safe dose and see if the drug shows any early signs of fighting the cancer. Researchers will monitor participants clo…

This study is testing an oral drug called HMPL-453 for people with advanced bile duct cancer inside the liver that has a specific genetic change (FGFR2 fusion/rearrangement) and has worsened after at least one prior treatment. The main goal is to see how well the drug shrinks tum…

This is an early-stage study testing a new drug called HMPL-A251 in adults with advanced or spreading HER2-positive solid tumors that cannot be removed by surgery. The main goals are to find a safe dose, check for side effects, and get an early look at whether the drug can help s…

This study is testing whether adding two newer drugs (surufatinib and camrelizumab) to standard chemotherapy works better for people with metastatic pancreatic cancer. It will compare the new four-drug combination against the current two-drug standard. The main goal is to see if …

This is the first study in people for an experimental oral drug called HMPL-506. Its main goals are to find a safe dose and see how the body processes the drug in adults with advanced blood cancers that have returned or not responded to prior treatments. The study will also look …