Hoffmann-la Roche

This early study tested a new drug called RO7565020 to see if it's safe for people with chronic hepatitis B. Researchers gave the drug to 60 healthy volunteers and hepatitis B patients to check for side effects and how the body processes it. The study was terminated after this in…

This study compared a new targeted drug called pralsetinib against standard chemotherapy for people with advanced lung cancer that has spread and carries a specific genetic change called a RET fusion. The trial involved 223 participants worldwide who had not yet received treatmen…

This study tested whether adding the immunotherapy drug atezolizumab to the targeted therapy cabozantinib works better than cabozantinib alone for people with advanced kidney cancer. It was for patients whose cancer had started growing again after a previous type of immunotherapy…

This study tested a combination of two immunotherapy drugs (tiragolumab and atezolizumab), given with or without standard chemotherapy, for people with certain stages of non-small cell lung cancer that could be removed by surgery. The goal was to see if giving these drugs both be…

This study tested an experimental drug called basmisanil in children aged 2 to 14 with Dup15q syndrome, a rare genetic disorder that causes developmental delays, seizures, and learning difficulties. The main goal was to see if the drug could safely improve daily living skills, co…

This study tested whether digital health tools, like apps or online platforms, could help people with specific cancers (lung or liver) better manage their symptoms and side effects while receiving standard drug treatments. It aimed to see if using these tools improved patients' q…