H. Lee Moffitt Cancer Center And Research Institute

This early-stage study tested a pill called Minnelide in adults whose acute myeloid leukemia (AML) had returned or didn't respond to prior treatments. The main goal was to find the highest safe dose and see how well the body tolerates it. Researchers also looked for signs that th…

This study tested an investigational oral drug called umbralisib in patients with chronic lymphocytic leukemia (CLL) who had never received treatment before. The goal was to see how well the drug worked to control the cancer and how safe it was for patients. The trial was small a…

This small, early-stage study tested the safety and effectiveness of a drug called siltuximab for adults with a rare blood cancer called large granular lymphocytic leukemia (LGLL). The goal was to see if the drug could reduce cancer cells and improve blood counts. The study was t…

This study tested whether combining two drugs (ibrutinib and pembrolizumab) could improve immune function and control chronic lymphocytic leukemia in high-risk patients who hadn't received prior treatment. The trial was designed to measure how well patients responded to the treat…

This early-stage trial tested whether a drug called fedratinib could safely prevent cancer from returning in patients with certain blood cancers (myeloproliferative neoplasms) after they received a stem cell transplant. The study aimed to find the safest effective dose and see if…