Experimental AML drug minnelide tested in early trial

NCT ID NCT03760523

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 32 times

Summary

This early-phase study tested the safety and best dose of a drug called Minnelide in 27 adults with acute myeloid leukemia (AML) that had returned or not responded to prior therapy. The goal was to find the highest safe dose and check for side effects. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.