Federation Francophone De Cancerologie Digestive

This study is testing whether giving two targeted cancer drugs—encorafenib and cetuximab—before surgery can shrink tumors in patients with a specific genetic mutation (BRAF V600E) in their localized colon or upper rectal cancer. The goal is to see if this 'neoadjuvant' treatment …

This study is for people with locally advanced anal cancer that has grown large or spread to nearby lymph nodes. It compares the current standard treatment (chemotherapy plus radiation) against a new approach that adds four cycles of a stronger chemotherapy drug combination *befo…

This study is for people with advanced stomach or gastro-esophageal cancer that has spread and has stopped responding to standard treatments. It will test if adding a drug called fruquintinib, which works by cutting off the tumor's blood supply, to an existing chemotherapy pill (…

This study aims to find biological markers that can predict which patients with a specific type of metastatic colorectal cancer will not respond to the immunotherapy drug pembrolizumab. It will follow 600 patients in France who are receiving this treatment to learn why it fails f…