Federation Francophone De Cancerologie Digestive

This study tests whether giving two targeted drugs (encorafenib and cetuximab) before surgery can shrink tumors in people with a specific genetic mutation (BRAF V600E) in colon or upper rectal cancer. About 30 participants will receive the drug combination for a short time, then …

This study tests whether adding fruquintinib to the standard oral chemotherapy trifluridine/tipiracil can help people with advanced stomach or gastro-esophageal junction cancer live longer. It is for patients who have already tried two or three prior treatments. The trial will co…

This study tests whether giving a specific chemotherapy (mDCF) before the usual chemoradiotherapy can improve outcomes for people with advanced anal cancer (stages T3-4 or N1). About 310 adults with this condition will be randomly assigned to either the standard treatment or the …

This study is for people with a specific type of advanced colorectal cancer called MSI. It aims to find out why about 20-30% of patients do not respond to the immunotherapy drug pembrolizumab. By studying 600 participants, researchers hope to identify markers that predict resista…