Ecog-acrin Cancer Research Group

This study tested whether adding hydroxychloroquine (a drug used for malaria) to standard targeted therapy (dabrafenib and trametinib) could help control advanced melanoma that has a specific gene change (BRAF V600E/K) and high LDH levels. The trial was stopped early after enroll…

This study tested two drugs, encorafenib and binimetinib, given before surgery to people with stage IIIB-D melanoma that had spread to lymph nodes. The goal was to see if the drugs could shrink or eliminate tumors before they were removed. Only 3 people enrolled before the study …

This study looked at whether two drugs, infliximab and intravenous immunoglobulin (IVIG), could help cancer patients with severe lung inflammation (pneumonitis) that didn't get better with steroids. The goal was to improve oxygen levels in the blood after 28 days. However, the st…