Ecog-acrin Cancer Research Group

This study tested whether giving two targeted drugs (encorafenib and binimetinib) before surgery could help shrink melanoma tumors in patients whose cancer had spread to nearby lymph nodes. The drugs aim to block signals that help cancer cells grow. The trial also tested whether …

This study tested whether adding the drug hydroxychloroquine to a standard two-drug treatment (dabrafenib and trametinib) could better control advanced melanoma that has a specific BRAF gene mutation. It aimed to see if the three-drug combo could delay cancer growth longer than t…

This study aimed to find a better treatment for a serious lung inflammation that can occur as a side effect of certain cancer immunotherapies when standard steroid treatment fails. It tested two different drug combinations (infliximab or intravenous immunoglobulin) in cancer pati…