Duke University
Clinical trials sponsored by Duke University, explained in plain language.
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App-Based exercise program aims to strengthen hearts in congenital disease
Disease control TerminatedThis study tests a remote, app-enabled exercise program designed for people aged 10 to 50 with congenital heart disease. Participants use a smartphone app with exercise modules and wearable devices to track heart rate and progress. The goal is to see if this approach can safely i…
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Can a common diabetes drug shield transplanted kidneys?
Disease control TerminatedThis study tested the drug empagliflozin (a diabetes medicine) in 20 people who had a kidney transplant, some with type 2 diabetes and some without. The goal was to see if the drug could help protect their heart and kidney function. The trial was stopped early, so the findings ar…
Phase: PHASE2 • Sponsor: Duke University • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Ear device aims to cut opioid use after liver transplant
Symptom relief TerminatedThis study tested a small device worn on the ear that uses mild electrical pulses to help control pain after a liver transplant. The goal was to see if it could reduce the need for strong painkillers like opioids. The study was stopped early and included 27 adults waiting for a l…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Frozen shoulder study: dry needling put to the test
Symptom relief TerminatedThis study looked at whether adding dry needling (inserting thin needles into muscle knots) to standard physical therapy exercises can reduce pain and improve shoulder movement in people with frozen shoulder. Ten adults with shoulder stiffness and pain were split into two groups:…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Breath test could replace needles for checking pulse oximeters
Knowledge-focused TerminatedThis study tests whether using expired (end-tidal) oxygen values, instead of arterial blood samples, can accurately measure the performance of pulse oximeters. Healthy adults aged 18–50 will undergo controlled oxygen desaturation sequences using a device called RespirAct, which a…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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New EyeCheck device put to the test for glaucoma monitoring
Knowledge-focused TerminatedThis study aimed to see if a new device called the EyeCheck monitor can measure eye pressure as accurately as standard tools in people with glaucoma or suspected glaucoma. Twenty-two participants used the device during a clinic visit. The study was stopped early, so results are l…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Ankle fracture study: does early washing protect joints?
Knowledge-focused TerminatedThis study looked at whether washing out the ankle joint with salt water within 48 hours of a fracture can lower inflammation and prevent cartilage breakdown. Researchers measured chemicals in the joint fluid of 41 adults before and after surgery. The goal was to see if early cle…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Athlete heart study halted after just one volunteer
Knowledge-focused TerminatedThis study aimed to find out how often COVID-19 affects the hearts of athletes. It planned to enroll college, professional, military, and Olympic athletes with or without COVID-19. Participants would answer daily health surveys for 30 days and share heart images for analysis. How…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC