Drugs For Neglected Diseases

This study tested a new single-dose oral drug called acoziborole in 208 adults with sleeping sickness, a deadly parasitic disease. Participants took three tablets once and were monitored for 18 months. The goal was to see if the drug could cure the infection at both early and lat…

This study tested a new drug called LXE408 for people with primary visceral leishmaniasis, a serious parasitic disease common in Ethiopia. 52 adults took part, and researchers checked if the drug could clear the parasite and improve symptoms by day 28. The goal was to see if LXE4…

This study tested a single dose of the experimental drug acoziborole in 35 children aged 1 to 14 with sleeping sickness (g-HAT). The goal was to see how the drug works in the body and if it is safe and effective. Researchers hope this oral treatment could replace older, more comp…

This study tested a new drug called LXE408 in 101 adults and teenagers with primary visceral leishmaniasis, a serious parasitic infection. The goal was to see if the drug could cure the infection by Day 28, meaning symptoms improved and no parasites were found in the spleen or bo…