New drug shows promise against deadly parasitic disease

NCT ID NCT05593666

First seen Jan 09, 2026 · Last updated May 08, 2026 · Updated 16 times

Summary

This study tested a new drug called LXE408 in 101 adults and teenagers with primary visceral leishmaniasis, a serious parasitic infection. The goal was to see if the drug could cure the infection by Day 28, meaning symptoms improved and no parasites were found in the spleen or bone marrow. The trial compared two different LXE408 treatment plans to each other and to a standard drug, AmBisome.

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Contacts and locations

Locations

  • DrugsNeglectedD Investigational Site

    Bihār, India

  • DrugsNeglectedD Investigational Site

    Patna, India

Conditions

Explore the condition pages connected to this study.