Dr. Inge Winter

This large study is testing if using stronger, third-line psychiatric medications right after a first treatment fails works better than the standard second-step approach. It involves over 1,200 adults with schizophrenia, major depression, or bipolar depression who did not get bet…

This study is testing if a more intense medication approach works better for people with bipolar depression when their first treatment fails. It will compare a stronger, three-drug combination given early against the usual second-choice treatment. The goal is to see if this faste…

This study is for adults with major depression whose first antidepressant didn't work well enough. It compares two next steps: switching to a different standard pill (usual care) versus quickly adding a stronger treatment, esketamine (a nasal spray or IV infusion), to a pill. The…

This study is testing if starting a more effective antipsychotic medication (clozapine) earlier helps people with schizophrenia better than the usual next-step treatments. It's for adults whose first medication didn't work well. The goal is to see if this faster, stronger approac…