Connecticut Children's Medical Center

This trial tests a procedure called FETO, where a small balloon is placed in the windpipe of a fetus with severe left congenital diaphragmatic hernia (CDH). The balloon blocks the airway temporarily, which may help the lungs grow larger before birth. The study includes pregnant w…

This study follows 900 children ages 6-17 who are newly diagnosed with Crohn's disease and starting anti-TNF therapy. Researchers will track healing of the intestine using blood tests, stool samples, colonoscopy, and MRI over one year. The goal is to understand why some children …

This study tests whether using a lung ultrasound score can help doctors decide when to give surfactant therapy to premature infants with respiratory distress syndrome. Surfactant is a substance that helps babies' lungs stay open, but giving it too late can reduce its benefit. The…

This study aims to see if a home lactate meter and a standard glucose meter give accurate readings compared to lab tests in people with glycogen storage disease types Ia, Ib, and XI. Ten participants will have an 8-hour hospital stay with hourly blood draws and finger-stick tests…

This study looks at a new, non-invasive test called nasal nitric oxide (nNO) testing to help diagnose primary ciliary dyskinesia (PCD), a rare lung condition. Researchers will collect data from 50 children and adults who have symptoms like chronic cough or nasal congestion. The g…

This study tests whether a program that addresses chronic pain can help teens with obesity stay in weight management treatment. Fifty adolescents aged 12-18 with both obesity and musculoskeletal pain will either receive the Pain and Weight Treatment (PAW) plus standard care, or p…

This study looks at whether yoga-based occupational therapy can improve body awareness and daily function in adolescents aged 11-21 with chronic pain. Participants will attend 8-12 weekly yoga sessions and complete questionnaires before and after treatment. The goal is to see if …

This study looks at whether adding blood flow restriction training (BFRT) to standard physical therapy helps teens recover strength and muscle size after ACL reconstruction. Forty teens who played sports before surgery will be randomly assigned to either standard rehab or standar…

This study looks at whether a quality-of-life questionnaire (OSA-18) can help parents of children with mild obstructive sleep apnea make treatment decisions. About 130 parents of children aged 3-12 with mild sleep apnea will take the survey. The goal is to see if the survey reduc…

This study looks at whether portable lactate monitors (like those used at home) give accurate results for people with glycogen storage disease type Ia. Ten participants will have their lactate and glucose levels measured by finger-stick and by standard lab tests. The goal is to s…

This study looks at whether teaching children and teens with inflammatory bowel disease (IBD) about ultra-processed foods (like packaged snacks and sugary drinks) can help them eat less of them. About 120 participants will complete online food diaries and receive either nutrition…