Simple nose test could speed up diagnosis of rare lung disease
NCT ID NCT05889013
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at a new, non-invasive test called nasal nitric oxide (nNO) testing to help diagnose primary ciliary dyskinesia (PCD), a rare lung condition. Researchers will collect data from 50 children and adults who have symptoms like chronic cough or nasal congestion. The goal is to see how well this simple nose test works compared to genetic testing and tissue biopsies in everyday medical practice.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could make diagnosing PCD faster and less invasive, reducing the need for more complex tests.
- What could go wrong
- This is an observational study with only 50 participants, so results may not apply to everyone. The test is not yet proven in everyday practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Pulmonary Division
RECRUITINGHartford, Connecticut, 06111, United States
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