Centre Hospitalier Universitaire Dijon

This study tests whether a chemotherapy regimen called FOLFIRINOX works better than the standard platinum-etoposide combination for people with a rare, fast-growing neuroendocrine cancer that has spread. About 218 adults with this cancer will be randomly assigned to one of the tw…

This study is testing whether a blood test for a protein called hPG80 can help detect neuroendocrine tumors (NETs) earlier in people with a rare genetic condition called MEN1. MEN1 patients often develop tumors in hormone-making glands, and current detection methods are limited o…

This study tests whether taking blood thinners for 12 weeks can prevent blood clots in people with autoimmune hemolytic anemia (AIHA), a rare disease where the immune system destroys red blood cells. About 72 adults with newly diagnosed or relapsed AIHA will receive either standa…

This study tests whether a non-invasive brain stimulation method called tDCS can reduce addictive gaming behavior in people who have lost control over their internet gaming. Fifty participants aged 12 and older will receive five sessions of tDCS or a fake treatment, and researche…

This study explores whether listening to rhythmic music before a language task can improve sentence understanding in adults aged 70 and older with age-related hearing loss. Researchers will compare the effects of rhythmic and non-rhythmic music on syntax skills. The goal is to fi…

This study will test if it's possible and acceptable to screen newborns for rare diseases using genome sequencing. About 5,000 newborns in France will take part. The goal is to see if this method can quickly find treatable or actionable rare diseases, helping doctors start care e…

This study aims to create a digital twin—a computer model—for people with chronic aortic dissection. The model will combine imaging, blood flow, and other data to better predict when the aorta might bulge or rupture. Researchers will enroll 400 adults with type A or chronic type …

This study looks at how a person's income, job, and social support affect their recovery after a stay in the intensive care unit (ICU). Researchers will follow 180 patients and their families to see who develops Post-Intensive Care Syndrome (PICS)—which includes physical weakness…

This study looks at skin cells called fibroblasts from people with scleroderma and compares them to cells from healthy volunteers. The goal is to find which genes are turned on or off in these cells, especially those linked to aging and inflammation. By understanding these differ…

This study is for 200 people who need surgery to repair an enlarged aorta (aneurysm). Researchers will use MRI scans before surgery and test the removed tissue in the lab to learn more about how the aorta's walls stretch and hold up. The goal is to help doctors better decide when…

This study looks at whether a simple ultrasound test, done while lifting a patient's legs, can predict how well they will handle extra fluids. The goal is to help doctors avoid giving too much fluid, which can harm the lungs, kidneys, and gut. About 100 adults in intensive care w…