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Digital twin tech could predict aortic rupture risk

NCT ID NCT07315178

Knowledge-focused Sponsor: Centre Hospitalier Universitaire Dijon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to build a digital twin—a computer model—for 400 people with chronic aortic dissection (a tear in the aorta). The model will combine imaging, blood flow, and other factors to better predict if an aneurysm will form and need surgery. The goal is to improve monitoring and catch dangerous changes earlier than current scans allow.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Nov 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Person who has given written consent * Age \> 18 years * Patient with type A aortic dissection with surgical indication for replacement * Patient with chronic type B aortic dissection, monitored and managed medically, not operated on Exclusion Criteria: * Persons not affiliated with or not covered by a social security scheme * Persons subject to legal protection measures (guardianship) * Persons subject to judicial protection measures * Pregnant women, women in labour or breastfeeding * Adults who are incapacitated or unable to give their consent * Contraindications to MRI: claustrophobia, non-MRI-compatible metal implants, suspected metal foreign body * Severe renal failure (clearance \<30ml/min according to Cockroft due to gadolinium injection) * Uncontrolled asthma * Patients with acute type A aortic dissection who died during or in the post-operative period following surgery to repair the dissection * Patients with a known allergy to gadolinium-based contrast agents * Patients treated for type B aortic dissection who underwent surgery

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic type B aortic dissection Type A aortic dissection with residual type B dissection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Chu Dijon Bourgogne

    RECRUITING

    Dijon, 21000, France