Centre Hospitalier St Anne

This trial investigates whether deep brain stimulation (DBS) — a surgical technique that uses implanted electrodes to regulate brain activity — can be a safe treatment for people with severe, long-lasting anorexia nervosa that has not responded to other therapies. The study will …

This phase 2 trial tests whether low-dose interleukin-2 (IL-2), an immune-modulating drug, can slow cognitive decline in people with early Alzheimer's disease. Forty participants will receive either IL-2 injections or a placebo for several months, and their cognitive function wil…

This study tests whether a short group therapy program (CBT) can help men in prison stop smoking. 202 participants will be randomly assigned to CBT, a health education session, or a waitlist. Researchers will check if they quit by measuring carbon monoxide levels at 1 and 3 month…

This study uses advanced PET scans to investigate how brain inflammation and tau protein buildup affect synaptic density in people with Alzheimer's disease. Researchers will compare Alzheimer's patients to healthy controls over two years, tracking changes in these brain markers. …