Centre Hospitalier Régional Metz-thionville

This study compares two types of corneal transplants—PKP and DSAEK—in 334 adults aged 50+ with advanced bullous pseudophakic keratopathy, a condition where the cornea swells and blurs vision. Participants are randomly assigned to one procedure and followed for 2 years to see whic…

This pilot study tests a new way to make a custom pressure orthosis for burn scars using 3D scanning and printing. About 25 adults with healing hypertrophic burn scars will get the device. The main goal is to see if the manufacturing process works and the orthosis fits safely.

This study is testing whether an artificial intelligence program can detect periapical lesions (infections at the tip of a tooth root) on common panoramic dental X-rays. The AI is trained using 3D cone-beam CT scans as the gold standard. Researchers will enroll 2000 patients who …

This study aims to create a detailed database of how healthy, precancerous, and cancerous skin interacts with light. Researchers will collect optical data from 140 patients with skin carcinomas or actinic keratoses. The goal is to identify unique light patterns (spectroscopic sig…

This study looks at whether a special brain wave monitor (EEG) can help doctors choose the right amount of sedation medicine for children who need a brain MRI. About 50 children under 5 years old (or older children who have trouble staying still) will receive a standard low dose …

This pilot study tests whether teens aged 13-17 who self-harm will use a small ear device that stimulates the vagus nerve. The device is used at home for 10-20 minutes daily over 8 weeks. The main goal is to see if teens stick with the treatment, not yet whether it works.

This study compares a lighter 'ambulatory' epidural to a standard one during childbirth, measuring how satisfied women feel about their labor and delivery. About 126 women with healthy, full-term pregnancies will fill out a questionnaire 2 days and 4 weeks after giving birth. The…

This study looks at two different pain-relief methods for people having open abdominal surgery (a midline cut). One group gets an epidural, the other gets numbing medicine injected into the belly muscles. The goal is to see which approach helps patients feel better and recover mo…

This study tests if hiding vision during treadmill walking helps people who had a stroke within the last 6 months improve their balance and walking. 36 participants will either walk with eyes covered or open, 3 times a week for 6 weeks. The goal is to see if blocking vision force…

This study looks at how quickly gadolinium, a contrast agent used in some MRIs, leaves the body through urine. Researchers will collect urine samples from 60 adults before and up to 2.5 hours after their MRI. The goal is to better understand the body's elimination of this substan…

This study is testing whether hospitals can safely stop using special contact precautions (like gowns and gloves) for a type of antibiotic-resistant bacteria called ESBLE in geriatric units. Researchers will compare infection rates before and after removing these precautions in o…

This study will compare how well patients see after three types of corneal transplants: DSAEK, UT-DSAEK, and DMEK. Researchers will follow 1,000 people who had surgery for Fuchs' endothelial corneal dystrophy or pseudophakic bullous keratopathy. They will measure vision, cell cou…

This study looks at how glucose spreads in the body of adults with severe burns (covering at least 30% of their skin). Researchers will measure glucose levels after a small injection over the first four days. The goal is to see if this measurement can help guide fluid treatment i…