Centre Hospitalier De Valence
Clinical trials sponsored by Centre Hospitalier De Valence, explained in plain language.
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Can a tiny adjustment to a mouthpiece make a big difference for sleep apnea?
Disease control CompletedThis study tested how small adjustments to a dental mouthpiece affect sleep apnea. Researchers worked with 20 adults who have moderate sleep apnea or severe apnea where a CPAP machine didn't work. They measured sleep breathing and daytime sleepiness as they moved the mouthpiece f…
Sponsor: Centre Hospitalier de Valence • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Which sleep apnea treatment better protects your heart?
Disease control CompletedThis study compared two standard treatments for obstructive sleep apnea to see which one better reduces the risk of serious heart and blood vessel problems. Researchers followed 172 adults already using either a CPAP breathing machine or a custom mouthpiece. They tracked whether …
Sponsor: Centre Hospitalier de Valence • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Singing and reflexology studied for cancer pain relief
Symptom relief CompletedThis study looked at whether four different well-being treatments could help reduce pain for people with cancer. It included 180 adult patients with any type of cancer who agreed to try sessions like foot reflexology, singing, socio-aesthetics, or sophrology. The main goal was to…
Sponsor: Centre Hospitalier de Valence • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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Scientists search for the cause of cancer Treatment's metallic taste
Knowledge-focused CompletedThis study aimed to understand why patients with head and neck cancer often experience a metallic taste before, during, and after treatment. Researchers followed 100 patients, collecting saliva samples and having them complete taste tests and questionnaires to identify potential …
Sponsor: Centre Hospitalier de Valence • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC
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French doctors create survey to understand Patients' swallowing struggles after cancer surgery
Knowledge-focused CompletedThis study aimed to create and test a French version of a patient survey about swallowing problems. It involved 225 adults in France who had their voice box and part of their throat surgically removed due to cancer. The goal was to better understand how swallowing difficulties af…
Sponsor: Centre Hospitalier de Valence • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Researchers map how sleep apnea devices shift your teeth
Knowledge-focused CompletedThis study aimed to understand how oral appliances used to treat sleep apnea affect tooth position over time. Researchers used 3D photography to measure dental movements in 180 adult patients already using these devices. The goal was to gather better data on this common side effe…
Phase: NA • Sponsor: Centre Hospitalier de Valence • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Scientists map the Tongue's 'Metallic' zones
Knowledge-focused CompletedThis study aimed to better understand metallic taste by testing where on the tongue people feel it most strongly. Researchers applied a small, safe amount of an iron solution to four specific spots on the tongues of 60 healthy volunteers. Participants then rated the intensity of …
Sponsor: Centre Hospitalier de Valence • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Researchers create french tool to measure jaw pain impact
Knowledge-focused CompletedThis study aimed to translate a questionnaire about jaw stiffness (trismus) into French and test how well it works. Trismus can be a painful side effect of cancer treatment or other conditions. The researchers had 310 French-speaking adults with trismus fill out the new questionn…
Sponsor: Centre Hospitalier de Valence • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:47 UTC