Biosplice Therapeutics, Inc.

This study looked at the long-term safety and effectiveness of lorecivivint, an experimental drug for knee osteoarthritis. It enrolled 276 adults who had already completed a previous study. The trial was terminated early, so results are limited. The goal was to see if the drug co…

This study tested an injection called lorecivivint for people with moderate to severe knee osteoarthritis. The goal was to see if it could improve cartilage health in the knee, measured by MRI scans. Only 13 people took part before the study was stopped early. The treatment aims …

This study tested an injection called lorecivivint for people with knee osteoarthritis. The goal was to see if it safely eases pain and improves knee function over three years in a real-world setting. The study was stopped early and included 72 adults aged 40 to 80.