Baylor Research Institute

This study tests whether using a tiny ultrasound camera inside the blood vessels during minimally invasive leg artery treatment leads to better results for people with peripheral artery disease. About 350 adults with leg pain or wounds from blocked arteries will be enrolled. The …

This study tests whether tirzepatide, a weight-loss drug, can help eliminate tiny amounts of cancer left after standard treatment in 48 patients with obesity or overweight and a high-risk type of early breast cancer. The goal is to see if weight loss leads to metabolic changes th…

This early-phase trial tests whether the drug bortezomib can make metastatic triple-negative breast cancer more sensitive to the immunotherapy pembrolizumab and chemotherapy cisplatin. About 20 women with advanced disease who have already received standard chemotherapy will recei…

This study compares two ways to guide a procedure that closes off a part of the heart to prevent strokes in people with atrial fibrillation. The standard method uses a probe down the throat (TEE), while the new method uses a probe inside the heart (ICE). The goal is to see if the…

This study tests if a special shockwave device, which uses sound waves to break up artery plaque, works as well as surgery for people with severely blocked leg arteries. About 60 adults with painful leg symptoms will be randomly assigned to get either the shockwave treatment or s…

This study aims to collect and store blood, tissue, urine, and stool samples from up to 10,000 cancer patients across Texas. Researchers will use these samples to study how the immune system responds to cancer treatments and find markers that predict which therapies work best. Th…

This study is collecting information from 14,000 people with peripheral artery disease (PAD) to compare outcomes between those who received a stent and those who received other treatments without a stent. Researchers will track events like repeat procedures, amputations, and walk…