New combo therapy aims to outsmart hard-to-treat breast cancer

NCT ID NCT04265872

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests whether giving the drug bortezomib first can make metastatic triple-negative breast cancer more sensitive to two other drugs (pembrolizumab and cisplatin). About 20 women with advanced breast cancer that has already been treated with standard chemotherapy will receive this sequence. The goal is to see if the tumors shrink or stop growing, and to study the cancer's genetic changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor University Medical Center, Baylor Charles A Sammons Cancer Center

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact