Autolus Limited

This program offers a special type of cell therapy (called obe-cel) to adults with a hard-to-treat form of leukemia (ALL) who have run out of standard options. The therapy is made from the patient's own blood cells, but the batch didn't meet commercial quality standards. The goal…

This early-stage study tests a new treatment called obecabtagene autoleucel (obe-cel) for people with severe lupus that hasn't responded to other therapies. Obe-cel uses a patient's own immune cells, modified to target and attack faulty B cells driving the disease. The trial aims…

This study tests a new treatment called obe-cel for children whose B-cell leukemia or lymphoma has come back or not responded to standard therapy. Obe-cel uses the child's own immune cells, which are modified in a lab to better recognize and attack cancer cells. The goal is to se…

This early-stage study tests whether a new cell therapy called obe-cel is safe for people with progressive multiple sclerosis (MS) that hasn't responded to other treatments. About 18 adults will receive chemotherapy followed by a single infusion of obe-cel, then be closely monito…

This study tests a new treatment called obe-cel for people with severe lupus that affects the kidneys and hasn't improved with standard therapies. Obe-cel is designed to destroy harmful immune cells that drive the disease. The trial will enroll 35 people aged 12 to 65 and check i…