Asian Institute Of Gastroenterology, India

This study tests whether taking pancreatic enzyme pills can help people with severe acute pancreatitis regain weight and improve nutrition. About 188 adults aged 18-60 who have lost significant weight due to the disease will receive either the enzyme or a placebo for 3 months. Th…

This study looks at adults hospitalized with a severe flare of ulcerative colitis that didn't get better with IV steroids. It compares taking two drugs together (infliximab and tofacitinib) versus taking just one of them. The goal is to see if the combo leads to faster symptom re…

This study tests a drug called esomeprazole, given through an IV, to prevent stress ulcers and acid reflux in 50 adults recovering from surgery in the intensive care unit (ICU). The goal is to see if it can keep stomach acid low enough to reduce the risk of bleeding. Participants…

This study tests a new device called TIES® that is implanted under the skin to help people with a permanent ileostomy or colostomy manage bowel movements more easily. Ten adults will receive the implant during stoma revision surgery and be followed for 16 weeks. The goal is to se…

This study compares two procedures—balloon dilation and per-oral endoscopic myotomy (POEM)—to see which better improves swallowing in children with achalasia cardia, a condition where the esophagus doesn't relax properly. About 70 children aged 3 to 17 will be randomly assigned t…

This study compares two ways of doing a surgery called POEM for people with type II achalasia, a condition that makes it hard to swallow. The standard method uses a long tunnel under the lining of the esophagus, while the experimental method uses a shorter tunnel. The goal is to …

This study will track over 2,300 people in India who need an ERCP procedure to treat bile duct or pancreas problems. Researchers want to find out how often pancreatitis happens after the procedure and how serious it is when standard safety steps are followed. The goal is to bette…

This study looks at whether simethicone, a medicine used to reduce gas before endoscopy, can make it harder to detect H. pylori, a stomach infection. About 100 adults who already have H. pylori will be tested before and after taking simethicone or a placebo. The goal is to see if…

This study checks if a computer model can accurately predict which Indian adults have colon polyps (growths that can turn into cancer). About 1,000 adults getting a colonoscopy will have their risk calculated by the model. If it works well, doctors could better decide who needs a…

This study compares two methods—pre-cut and double guidewire—used when doctors have trouble getting a tube into the bile duct during an ERCP procedure. About 840 adults with bile duct problems will take part to see which technique works better and causes fewer side effects like p…

This study will examine 4,000 adults aged 40 and older in India using high-definition endoscopy to find early stomach cancer and precancerous changes. Participants are people already scheduled for an upper GI endoscopy due to digestive symptoms. The goal is to learn how common th…