Aids Malignancy Consortium

This study tested whether the HPV vaccine can reduce the chance of developing high-grade cervical lesions (precancerous changes) in women living with HIV. About 536 women received either the HPV vaccine or a placebo. The goal was to see if the vaccine helps the immune system figh…

This study tested a drug called pomalidomide in 26 HIV-positive people with Kaposi sarcoma, a type of skin cancer. The drug works by boosting the immune system and stopping tumor growth. The goal was to see if it could shrink tumors and control the disease safely.

This study tested a DNA-based vaccine called VGX-3100 in 44 HIV-positive adults with high-grade anal precancer caused by HPV types 16 or 18. The vaccine was given with a mild electrical pulse (electroporation) to help cells absorb it and boost the immune response. The goal was to…

This study looked at whether removing small, early-stage anal cancers with local surgery alone is safe and effective for people with HIV. The goal was to see if this less invasive approach could avoid the need for radiation or chemotherapy. Sixteen participants were followed for …

This study looked at how well people with AIDS-related Kaposi sarcoma felt during treatment with two chemotherapy drugs, vincristine and bleomycin. Ten participants in Tanzania filled out quality-of-life surveys over three months. The goal was to understand how the treatment affe…

This study looked back at 30 people with HIV who had already received CAR T-cell therapy for certain blood cancers. Researchers collected standard medical data to see what side effects occurred and how the immune system changed over time. The goal was to learn more about safety a…