Aids Malignancy Consortium

This study tested whether nelfinavir, a medication originally developed for HIV, could help treat Kaposi sarcoma skin cancer. Researchers gave 36 participants with Kaposi sarcoma increasing doses of the drug to see if it could shrink their tumors. The trial measured how many peop…

This study tested whether the drug pomalidomide could safely help control Kaposi sarcoma, a cancer that often affects people with HIV. It involved 26 HIV-positive adults in sub-Saharan Africa who took the drug daily in repeating cycles. Researchers measured how well the drug shra…

This study tested whether the HPV vaccine could help prevent high-grade cervical lesions from developing or returning in women living with HIV. 536 HIV-positive women who also had HPV received either the actual vaccine or a placebo (saltwater shot) after their cervical lesions we…

This small, completed pilot study aimed to understand how standard chemotherapy drugs affect the daily life and well-being of people with AIDS-related Kaposi sarcoma in Tanzania. Ten participants receiving treatment were followed to see if their quality of life improved. The main…

This study aims to gather information on how well a cancer treatment called CAR T-cell therapy works for people living with HIV who also have certain blood cancers. Researchers will collect standard medical data from about 30 patients who have already received this therapy. The g…

This study aimed to understand how many people with HIV develop cancer and what types of cancer they get. Researchers collected information from 462 patients at US clinics to see patterns in cancer care and learn why some patients do or don't join cancer treatment trials. The stu…