⭐️ CURE ⭐️
Recruiting now
Phase: PHASE2, PHASE3 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China
A large trial testing blinatumomab and venetoclax to improve survival and reduce side effects in children with intermediate/high-risk B-cell ALL.
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⭐️ CURE ⭐️
Completed
Phase: PHASE1 • Sponsor: University of Pennsylvania
A Phase I trial testing a gene therapy injection for vision loss caused by RPE65 mutations, aiming to restore sight in Leber congenital amaurosis.
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⭐️ CURE ⭐️
Not yet recruiting
Phase: PHASE1 • Sponsor: Daniel Bauer
A pilot trial testing gene editing of blood stem cells to increase fetal hemoglobin and potentially cure sickle cell disease in 5 participants.
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⭐️ CURE ⭐️
Not yet recruiting
Phase: NA • Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
This trial tests a 'shock-and-kill' strategy combining two immune therapies to reduce the HIV reservoir, aiming toward a cure.
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⭐️ CURE ⭐️
Not yet recruiting
Phase: PHASE1, PHASE2 • Sponsor: University Hospital, Bordeaux
A trial testing whether adding venetoclax to standard chemotherapy and midostaurin improves remission rates in FLT3-mutated acute myeloid leukemia.
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⭐️ CURE ⭐️
Not yet recruiting
Phase: PHASE1 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China
A phase 1 trial testing a new CAR-T cell therapy, KIV-318, for relapsed/refractory multiple myeloma. It aims to assess safety and early signs of effectiveness.
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⭐️ CURE ⭐️
Not yet recruiting
Phase: PHASE2 • Sponsor: Prince of Wales Hospital, Shatin, Hong Kong
A phase 2 trial testing whether a one-time gene therapy called HGI-001 can free people with transfusion-dependent β-thalassemia from needing regular blood trans
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⭐️ CURE ⭐️
Not yet recruiting
Phase: PHASE3 • Sponsor: Kringle Pharma, Inc.
A phase 3 trial testing whether an injected drug, KP-100IT, can help people with severe spinal cord injuries regain movement and sensation.
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⭐️ CURE ⭐️
Completed
Phase: PHASE2 • Sponsor: Brii Biosciences Limited
A phase 2 trial testing whether a combination of two experimental drugs can clear chronic hepatitis B infection and allow patients to stop standard therapy.
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⭐️ CURE ⭐️
ENROLLING_BY_INVITATION
Sponsor: N.N. Alexandrov National Cancer Centre
A trial testing whether anti-CD19 CAR-T cell therapy can induce remission in patients with refractory systemic lupus erythematosus.
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