Radiation that adapts: can it spare swallowing muscles in head and neck cancer?
NCT ID NCT06214611
First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time
Summary
Researchers are testing adaptive radiotherapy, a radiation technique that adjusts the treatment plan to changes in tumor shape and position during a course of treatment. The trial enrolls 30 adults with head and neck cancer who are scheduled for radiotherapy. The goal is to see whether adaptive radiotherapy can maintain tumor coverage while reducing radiation dose to organs at risk, potentially lowering swallowing problems.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- adaptive radiotherapy, a radiation technique that adjusts the treatment plan to changes in tumor shape and position
- What this could lead to
- If it works, adaptive radiotherapy could become a standard option for head and neck cancer, helping spare healthy organs and reduce swallowing problems.
- What could go wrong
- This is a small study with 30 participants, so results may not apply broadly. Adaptive radiotherapy requires extra imaging and planning, which can be complex and time-consuming.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Oct 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. ECOG 0-1 2. Histopathology confirmation 3. Compliance 4. Tumor in the head and neck region 5. Indication for radiotherapy Exclusion Criteria: 1\. Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) West
Essen, Germany / NRW, 45147, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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