Radiation that adapts: can it spare swallowing muscles in head and neck cancer?

NCT ID NCT06214611

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time

Summary

Researchers are testing adaptive radiotherapy, a radiation technique that adjusts the treatment plan to changes in tumor shape and position during a course of treatment. The trial enrolls 30 adults with head and neck cancer who are scheduled for radiotherapy. The goal is to see whether adaptive radiotherapy can maintain tumor coverage while reducing radiation dose to organs at risk, potentially lowering swallowing problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
adaptive radiotherapy, a radiation technique that adjusts the treatment plan to changes in tumor shape and position
What this could lead to
If it works, adaptive radiotherapy could become a standard option for head and neck cancer, helping spare healthy organs and reduce swallowing problems.
What could go wrong
This is a small study with 30 participants, so results may not apply broadly. Adaptive radiotherapy requires extra imaging and planning, which can be complex and time-consuming.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Nov 2023

Finished

Oct 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. ECOG 0-1 2. Histopathology confirmation 3. Compliance 4. Tumor in the head and neck region 5. Indication for radiotherapy Exclusion Criteria: 1\. Pregnancy

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) West

    Essen, Germany / NRW, 45147, Germany

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