UPPER TRACT UROTHELIAL CARCINOMA
Clinical trials for UPPER TRACT UROTHELIAL CARCINOMA explained in plain language.
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Could a drug combo spare bladder cancer patients from surgery?
Disease control Not yet recruitingThis phase 2 trial tests a combination of two drugs, enfortumab vedotin and pembrolizumab, given before surgery to people with muscle-invasive bladder cancer or upper tract urothelial carcinoma. The goal is to see if the drugs can shrink or eliminate the cancer enough that some b…
Matched conditions: UPPER TRACT UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New drug duo aims to fight kidney cancer without losing the kidney
Disease control Not yet recruitingThis study tests a two-drug treatment (disitamab vedotin plus tislelizumab) for people with a rare, aggressive cancer of the upper urinary tract that has a specific marker (HER2-positive). The goal is to shrink the tumor so that the kidney can be saved, avoiding complete removal.…
Matched conditions: UPPER TRACT UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: RenJi Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New combo therapy aims to save kidneys in High-Risk cancer patients
Disease control Not yet recruitingThis study tests a kidney-sparing approach for people with high-risk upper tract urothelial carcinoma, a cancer in the kidney or ureter. Instead of removing the whole kidney, participants get endoscopic surgery, targeted radiotherapy, and two drugs (disitamab vedotin and toripali…
Matched conditions: UPPER TRACT UROTHELIAL CARCINOMA
Sponsor: Peking University First Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New hope for rare kidney cancer: targeted drug plus radiation may replace chemo
Disease control Not yet recruitingThis study tests a new treatment for people with a rare cancer of the upper urinary tract (UTUC) that has spread beyond the kidney. Participants must have had surgery and cannot take standard chemo due to health reasons. They will receive either a targeted drug (disitamab vedotin…
Matched conditions: UPPER TRACT UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Peking University First Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New drug duo aims to shrink upper tract bladder cancer before surgery
Disease control Not yet recruitingThis study tests whether giving two drugs (toripalimab and 9MW2821) before surgery can improve outcomes for people with localized upper tract urothelial carcinoma, a type of cancer in the kidney or ureter. About 40 adults will be randomly assigned to either the drug combo followe…
Matched conditions: UPPER TRACT UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Peking University Third Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New scope technique could simplify cancer monitoring after Kidney-Sparing surgery
Knowledge-focused Not yet recruitingThis pilot study will test whether a flexible scope inserted into the urinary tract (ureterorenoscopy) under local anesthesia is safe and feasible for monitoring upper tract urothelial cancer in 10 people who have had kidney-sparing surgery. The main goal is to see if the procedu…
Matched conditions: UPPER TRACT UROTHELIAL CARCINOMA
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC