UNCONTROLLED HYPERTENSION
Clinical trials for UNCONTROLLED HYPERTENSION explained in plain language.
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Zapping kidney nerves may tame tough blood pressure
Disease control CompletedThis study tested a device that uses ultrasound to calm overactive nerves in the kidneys, which can drive high blood pressure. Researchers enrolled 44 people with stage 3 chronic kidney disease and uncontrolled hypertension. Half received the real procedure, half a sham, to see i…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: NA • Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New pill may help when blood pressure meds aren't enough
Disease control CompletedThis study tested a new drug called baxdrostat in 326 adults whose high blood pressure was not controlled even with two or more medications. Participants took either 1 mg, 2 mg of baxdrostat, or a placebo daily for 12 weeks. The main goal was to see if baxdrostat could lower syst…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Ear device zaps nerves to tame stubborn high blood pressure?
Disease control CompletedThis pilot study tested a device that sends mild electrical pulses to a nerve in the ear, aiming to lower blood pressure in people whose hypertension is not controlled by medication. 63 adults took part, and the device was compared to a sham (fake) version. The goal was to see if…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: NA • Sponsor: Queen Mary University of London • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New drug baxdrostat aims to tame stubborn high blood pressure
Disease control CompletedThis Phase 3 trial tested a daily pill called baxdrostat in about 800 adults whose blood pressure stays high even when taking two or more other medications. Participants received either 1 mg, 2 mg, or a placebo for 12 weeks. The main goal was to see if baxdrostat could safely low…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New blood pressure Drug's safety checked in cortisol study
Knowledge-focused CompletedThis study tested whether baxdrostat, an experimental drug for high blood pressure, affects the body's stress hormone cortisol. 48 adults with uncontrolled hypertension took baxdrostat or a placebo for 8 weeks. Researchers measured cortisol levels before and after a stimulation t…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE2 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC