UNCONTROLLED HYPERTENSION
Clinical trials for UNCONTROLLED HYPERTENSION explained in plain language.
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Could a gentle zap to the neck tame stubborn high blood pressure?
Disease control CompletedThis study tested a non-invasive device that stimulates the vagus nerve (a key nerve in the body) to see if it can safely help lower blood pressure in adults whose high blood pressure is not well-controlled by medication. 63 adults took part, and the device was compared to a sham…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: NA • Sponsor: Queen Mary University of London • Aim: Disease control
Last updated May 17, 2026 04:28 UTC
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Kidney nerve zapping shows promise for tough blood pressure in kidney disease
Disease control CompletedThis study tested a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it can lower blood pressure in people with chronic kidney disease (stage 3) whose blood pressure remains high despite taking 1-5 medications. 44 participa…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: NA • Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New pill may help when blood pressure meds aren't enough
Disease control CompletedThis study tested a new drug called baxdrostat in about 800 adults with high blood pressure that remains high despite taking two or more medications. Participants took either 1 mg, 2 mg, or a placebo pill daily for 12 weeks. The goal was to see if baxdrostat could safely lower bl…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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New pill aims to lower stubborn high blood pressure
Disease control CompletedThis study tested a new drug called baxdrostat in 326 adults whose high blood pressure was not controlled by two or more medications. Participants took either 1 mg, 2 mg of baxdrostat, or a placebo daily. The main goal was to see if baxdrostat could lower sitting systolic blood p…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Blood pressure Drug's impact on stress hormone examined
Knowledge-focused CompletedThis study looked at how baxdrostat, a potential new blood pressure medicine, affects the body's stress hormone cortisol in people with uncontrolled high blood pressure. 48 adults took either baxdrostat or a placebo for 8 weeks. Researchers measured cortisol levels before and aft…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE2 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 11, 2026 20:48 UTC