TYPE1DIABETES

This study tests whether a probiotic called Lactiplantibacillus plantarum 299v can reduce inflammation and help preserve the body's ability to produce insulin in people recently diagnosed with type 1 diabetes. About 60 participants aged 3-45 will take the probiotic or a placebo f…

This study tests a single infusion of stem cells from donated umbilical cord tissue (Wharton's jelly) in 66 children and teens aged 7–21 who were diagnosed with type 1 diabetes within the last 6 months. The goal is to see if the treatment is safe and can help the body produce mor…

This study tests whether taking a probiotic supplement can reduce inflammation in children and teens (ages 5-17) recently diagnosed with type 1 diabetes. The goal is to see if changing gut bacteria can slow the disease's progression. Participants receive either a probiotic or a p…

This study tests whether cyclophosphamide, a drug that calms the immune system, can reduce insulin needs in people with a rare condition that causes fat loss (lipodystrophy) and type 1 diabetes. Ten participants will receive the treatment, and researchers will measure how much in…

This study looks at whether giving pasteurized donor milk instead of formula to newborns at risk for low breastfeeding helps them breastfeed longer and more exclusively. About 112 infants born to diabetic mothers, small for gestational age, or late preterm are randomly assigned t…

This study looks at whether eating very little gluten (less than 3 grams per day) during the first three years of life can lower the chance of developing celiac disease in children who are genetically at risk. Over 1,100 children with specific genes are being followed until age 7…