TYPE II DIABETES MELLITUS

This study tests a community-based program to help prevent and control type 2 diabetes in rural Kabul, Afghanistan. About 250 adults aged 20 and older will take part in group meetings to learn about diabetes. The goal is to see if the program is practical and well-liked by the co…

This study looks at how safe and well-tolerated the diabetes medicine empagliflozin (taken with or without metformin) is for people with type 2 diabetes in Pakistan. About 2,000 adults aged 18 to 65 whose blood sugar is not well controlled will take the drug and be monitored for …

This study tests whether personalized marketing messages and discounts can encourage people with prediabetes or type 2 diabetes to switch from refined grains to whole grains when shopping for groceries online. About 216 adults aged 45-70 from the Philadelphia area who already sho…

This study tests a new weekly injection called GL0034 in 285 adults with type 2 diabetes who are overweight or obese. Participants will receive either the study drug or a placebo for about 36 weeks. The main goal is to see if GL0034 helps lower blood sugar levels more than a plac…

This early-stage study tests a new stem cell therapy made from fetal cells for people with type 2 diabetes. The goal is to see if it is safe and can help improve blood sugar control. About 30 adults with poorly controlled diabetes will receive the treatment and be monitored for s…

This study tests a new medication, CX11, for people with type 2 diabetes who need better blood sugar control despite taking metformin. About 240 adults will receive different doses of CX11 or a placebo for 24 weeks to see if it safely lowers blood sugar. The goal is to find the b…

This study tests whether community-led learning groups can help prevent and control type 2 diabetes in rural Pakistan. Over 12,000 adults aged 20 and older from Peshawar and Swabi will take part. The approach, called Participatory Learning and Action, has worked in Bangladesh and…

This study tests whether combining sensory and motor exercises can reduce pain and improve balance in postmenopausal women with nerve damage (polyneuropathy). About 100 women with type 2 diabetes and numbness in their arms and legs will be enrolled. The goal is to see if these ex…

This study tests a single dose of a new long-acting diabetes medicine (GL0034) in 40 adults with different levels of kidney function. Researchers want to see if kidney problems change how the drug moves through the body. The goal is to find the right dose for people with kidney i…