TREATMENT-RESISTANT SCHIZOPHRENIA
Clinical trials for TREATMENT-RESISTANT SCHIZOPHRENIA explained in plain language.
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Brain pacemaker trial aims to quiet voices in Treatment-Resistant schizophrenia
Disease control Not yet recruitingThis pilot study will test whether deep brain stimulation (DBS) can help people with schizophrenia who still hear voices and have delusions despite trying multiple medications. Fifteen adults will have electrodes placed in a brain region linked to schizophrenia symptoms. The goal…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a nasal spray of stem cell 'Messages' ease Schizophrenia's toughest symptoms?
Symptom relief Not yet recruitingThis early-phase pilot study will test whether a nasal spray containing exosomes from human dental stem cells is safe and feasible for people with treatment-resistant schizophrenia who have persistent negative symptoms like social withdrawal and lack of emotion. Fifteen long-term…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: EARLY_PHASE1 • Sponsor: Zigong Mental Health Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:04 UTC
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Can magnetic pulses sharpen the mind in schizophrenia?
Symptom relief Not yet recruitingThis study compares two types of brain stimulation—accelerated theta burst and high-frequency TMS—against a sham (fake) treatment to see if they can improve cognitive problems like memory and attention in people with treatment-resistant schizophrenia. Ninety adults on clozapine w…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: NA • Sponsor: All India Institute of Medical Sciences, Bhubaneswar • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Brain boost: exercise and zaps may sharpen mind in tough schizophrenia cases
Symptom relief Not yet recruitingThis study tests whether aerobic exercise, alone or with a gentle brain stimulation technique called tDCS, can improve thinking and memory in people with treatment-resistant schizophrenia. About 160 participants will be assigned to exercise, tDCS plus exercise, or a control group…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: NA • Sponsor: Kit Wa Chan • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC