TNBC
Clinical trials for TNBC explained in plain language.
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New drug targets rare cancer mutation in 300-patient trial
Disease control Recruiting nowThis study tests a new drug called PC14586 (rezatapopt) in people with advanced or spreading solid tumors that have a specific change in the TP53 gene (Y220C mutation). The goal is to see if the drug is safe and works against these cancers. About 300 adults (and some teens after …
Matched conditions: TNBC
Phase: PHASE1, PHASE2 • Sponsor: PMV Pharmaceuticals, Inc • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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New hope for advanced breast cancer patients: expanded access to investigational drug leronlimab
Disease control AVAILABLEThis program offers investigational leronlimab to adults with advanced or metastatic triple-negative breast cancer who have run out of standard treatment options. Participants must have confirmed HR-/HER2- cancer and have progressed on prior therapy. The goal is to provide potent…
Matched conditions: TNBC
Sponsor: CytoDyn, Inc. • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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Smart CAR t cells take aim at Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new treatment called A2B395 for adults with advanced solid tumors (like colorectal, lung, breast, and kidney cancers) that have not responded to standard therapy. The treatment uses specially engineered immune cells designed to kill cancer cells while protectin…
Matched conditions: TNBC
Phase: PHASE1, PHASE2 • Sponsor: A2 Biotherapeutics Inc. • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New drug enzelkitug takes on advanced cancers in first human trial
Disease control Recruiting nowThis study is testing a new drug, enzelkitug, for people with advanced solid tumors that have spread or cannot be removed by surgery. The trial includes many cancer types like lung, head and neck, melanoma, breast, and others. The main goal is to check the drug's safety and find …
Matched conditions: TNBC
Phase: PHASE1 • Sponsor: Genentech, Inc. • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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New drug combo shows promise in early aggressive breast cancer trial
Disease control Recruiting nowThis study tests whether adding the drug ivonescimab to standard chemotherapy before surgery can improve outcomes for people with early-stage triple-negative breast cancer. About 34 participants will receive the combination every three weeks for six cycles, then undergo surgery. …
Matched conditions: TNBC
Phase: PHASE2 • Sponsor: Cedars-Sinai Medical Center • Aim: Disease control
Last updated May 11, 2026 20:49 UTC