TIBIAL FRACTURES

This study compares a standard metal rod (nail) used to fix shinbone fractures with a new 'micromotion' nail that allows a tiny amount of movement at the break. Researchers want to see if the new nail helps bones heal faster and with fewer problems. About 100 adults with stable s…

This study tests whether special crutch tips that measure how much weight you put on your leg can help a broken shinbone heal better. Thirty people who had surgery for a tibial fracture will use the smart tips for up to 24 weeks, following a personalized walking plan based on CT …

This study tests a new type of metal nail coated with a noble metal alloy to fix broken shin bones (tibia fractures). The goal is to see if it reduces the chance of infection compared to standard uncoated nails. About 500 adults with high-risk fractures will be followed for 12 mo…

This study tests whether coating a metal rod (intramedullary nail) with antibiotics (vancomycin and gentamicin) can prevent deep infections in people with severe open tibia fractures. About 484 adults with Gustilo Type II or III open tibia fractures will be randomly assigned to r…

This study tests whether placing an antibiotic depot directly into the bone during surgery can prevent infections in people with severe open tibia fractures. About 497 adults with type II or III open fractures will be randomly assigned to get either the antibiotic depot plus stan…

This study compares two types of physical therapy for people with a broken shinbone. One group will do low-weight exercises while wearing a blood flow restriction cuff on their leg. The other group will do the same exercises without the cuff. Researchers will measure muscle stren…