New coated nail aims to stop bone infections after leg fractures
NCT ID NCT05022485
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new type of metal nail coated with a noble metal alloy to fix broken shin bones (tibia fractures). The goal is to see if it reduces the chance of infection compared to standard uncoated nails. About 500 adults with high-risk fractures will be followed for 12 months to check infection rates and bone healing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
noble metal alloy-coated intramedullary nail
What this could lead to
If it works, this could reduce the risk of serious bone infections after tibia fracture surgery, leading to faster healing and fewer complications.
What could go wrong
This is a mid-stage trial with a retrospective control group, which may introduce bias. The coating might not significantly lower infection rates, and there could be unknown risks with the new material.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AOU Policlinico di Bari
RECRUITINGBari, 70124, Italy
Contact Email: •••••@•••••
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Azienda Ospedaliero-Universitaria Careggi
RECRUITINGFlorence, 50134, Italy
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Groote Schuur Hospital
RECRUITINGCape Town, 7935, South Africa
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Valle de Hebrón
RECRUITINGBarcelona, Catalonia, 08035, Spain
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Contact Email: •••••@•••••
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Hôpital Ambroise-Paré
RECRUITINGBoulogne-Billancourt, 92100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpitaux Universitaires de Marseille Nord
RECRUITINGMarseille, 13915, France
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Kantonsspital Winterthur
RECRUITINGWinterthur, Canton of Zurich, 8400, Switzerland
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King's College Hospital NHS Trust
RECRUITINGLondon, SE5 9RS, United Kingdom
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Leeds General Infirmary
RECRUITINGLeeds, LS1 3EX, United Kingdom
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, EH16 4SA, United Kingdom
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The Royal London Hospital
RECRUITINGLondon, E1 1FR, United Kingdom
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Tirolkliniken Innsbruck
RECRUITINGInnsbruck, 6020, Austria
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Tygerberg Hospital
RECRUITINGCape Town, 7505, South Africa
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitätsklinikum Leipzig
RECRUITINGLeipzig, 04103, Germany
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Universitätsklinikum Marburg
RECRUITINGMarburg, Hesse, 35039, Germany
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Universitätsklinikum Regensburg
RECRUITINGRegensburg, 93053, Germany
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