Speed walking after a broken leg: new study tests HIIT for faster recovery

NCT ID NCT05274022

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Not a trial. The treatment could once be requested outside a study, but no longer can.
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The treatment has been approved, so it is available normally rather than through this programme.

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First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a high-intensity interval training (HIIT) walking program for people recovering from a broken thigh or shin bone. 66 adults aged 18-50 who had surgery for their fracture took part. The goal was to see if this type of exercise could improve their physical function and ability to do daily activities.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

66 people

The number who actually took part.

Started

Mar 2022

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Ability to read and speak English * Acute orthopedic injury to the femoral or tibial shaft requiring surgical fixation with an intramedullary rod * Age 18-50 years of age Exclusion Criteria: * History of chronic pain defined as pain lasting more than 3 months and bothersome at least half the days over the past 6 months that started before the fracture * Moderate or severe traumatic brain injury * Initial treatment requiring amputation * Not employed at the time of the accident at least 20 hours per week. * Spinal cord injury * History of schizophrenia, dementia or neurologic disorder with peripheral dysfunction * Non ambulatory or limited ability to walk without an assistive device prior to the fracture * Multiple trauma that prevents early weight bearing * Current Pregnancy * Unable to participate in or complete in-person follow-up visits or therapy sessions * In outpatient Physical Therapy at the start of the intervention * Use of an assistive device to walk for community ambulation at the 10-12 weeks post hospital discharge time point

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kentucky

    Lexington, Kentucky, 40506, United States

  • Vanderbilt University

    Nashville, Tennessee, 37203, United States

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