THYROID NODULE

This study looks at whether closely monitoring small thyroid nodules (under 2 cm) with regular ultrasounds is a safe and effective alternative to immediate surgery. The goal is to avoid unnecessary operations and the need for lifelong thyroid medication. Researchers will follow 1…

This study tests whether an herbal liquid called Prunella oral liquid can safely shrink benign (non-cancerous) thyroid nodules. About 234 adults with solid nodules between 1 and 3 cm will take either the herb or a placebo for 9 months. The main goal is to see if the nodule volume…

This study is testing a new device that uses electrical pulses to shrink benign (non-cancerous) thyroid nodules without surgery. About 100 adults with symptomatic thyroid nodules will receive the treatment and be followed for up to 12 months to see how much the nodule shrinks and…

This study aims to develop an AI tool that combines ultrasound images and cell slide pictures to more accurately predict whether a thyroid nodule is cancerous. Researchers will enroll 396 people whose initial lab tests were unclear (called Bethesda III). The goal is to reduce unn…

This study tests whether adding contrast-enhanced ultrasound to standard ultrasound can more accurately diagnose thyroid cancer. Researchers compare two scoring methods in 800 adults with thyroid nodules. The goal is to see which method better identifies cancer and reduces the nu…

This study tests a minimally invasive procedure called radiofrequency ablation (RFA) for LatinX adults with benign thyroid nodules that cause discomfort or cosmetic issues. RFA uses heat to shrink the nodule without surgery. The goal is to see if it safely reduces symptoms and no…

This study is testing a new type of ultrasound called multiparametric ultrasound (mpUS) to see if it can give more detailed information about tissue than standard ultrasound. Researchers will compare mpUS images to regular ultrasound and other tests in people at high risk for pan…

This study looks back at 600 adults who had their thyroid removed at Minia University Hospital over 10 years. The goal is to find out which patients are more likely to develop low calcium levels after surgery, a common complication. By identifying risk factors like age, lab resul…

This study involves 300 people with thyroid cancer or benign nodules who will undergo surgery through the mouth or under the chin. Researchers want to improve a prediction model that helps doctors know how difficult the surgery will be, so they can better plan and train for it. T…

This pilot study compares two approaches for managing thyroid nodules that look suspicious on ultrasound: immediate biopsy (usual care) versus active monitoring with regular ultrasounds. The goal is to see which approach leads to less anxiety and better quality of life for patien…

This study is testing a decision aid for people with small thyroid nodules that are either cancerous or have a chance of being cancerous. The goal is to see if the tool helps patients choose a treatment that matches their personal values. About 134 participants will fill out surv…

This study aims to develop and test a scoring system called RTAS to evaluate how well surgeons perform robotic thyroidectomy, a surgery to remove all or part of the thyroid gland. The study will include 200 adults with thyroid cancer or benign thyroid nodules who are having this …