THYROID EYE DISEASE (TED)

This early-stage trial is testing a new drug called cizutamig in 38 adults with active, moderate-to-severe thyroid eye disease. The main goal is to see if the drug is safe and tolerable, while also checking how the body processes it and whether it shows any signs of helping the c…

This study tests whether taking a statin (atorvastatin) and vitamin D can calm inflammation and reduce eye bulging in people with active thyroid eye disease. 120 adults will be randomly assigned to standard care alone, statin plus standard care, vitamin D plus standard care, or b…

This study tests an oral medication called tofacitinib in 8 people with moderate-to-severe thyroid eye disease who did not improve with or could not take steroids. The drug works by blocking inflammation pathways. Researchers will check if it reduces eye bulging and other symptom…

This study tests a drug called MHB018A for people with moderate-to-severe thyroid eye disease, a condition that can cause bulging eyes and discomfort. About 258 adults who completed earlier studies will receive injections every 4 weeks. The main goal is to see if the drug reduces…

This Phase 3 trial tests an injection called MHB018A for people with chronic moderate-to-severe thyroid eye disease. The drug targets a protein linked to inflammation and eye bulging. About 150 adults will receive either the drug or a placebo every 4 weeks for 6 months. The main …

This early-stage trial is testing a new drug called GenSci098 in 76 adults with active thyroid eye disease (TED). The main goal is to check the drug's safety and how the body processes it at different doses. Participants will receive either the drug or a placebo as a shot under t…

This study tests a new drug called ZL-1109 for people with moderate to severe thyroid eye disease, a condition that causes eye bulging and discomfort. About 99 Chinese adults will receive either the drug or a placebo to see if it safely reduces eye bulging by at least 2 millimete…