Promising new shot for bulging eyes moves to final testing
NCT ID NCT07262476
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called MHB018A for people with moderate-to-severe thyroid eye disease, a condition that can cause bulging eyes and discomfort. About 258 adults who completed earlier studies will receive injections every 4 weeks. The main goal is to see if the drug reduces eye bulging by at least 2 millimeters after 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MHB018A injection
What this could lead to
If successful, this could provide a new treatment option to reduce eye bulging and control symptoms in people with thyroid eye disease.
What could go wrong
This is an open-label extension study, so results may be less reliable than blinded trials. The treatment may not work for everyone and could have side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, 201419, China
Contact Phone: •••-•••-•••• Email: •••••@•••••