SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Clinical trials for SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) explained in plain language.
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Could CAR-T cells tame autoimmune diseases? new safety trial launches
Disease control Not yet recruitingThis early-stage study tests whether a single infusion of a patient's own modified immune cells (CAR-T cells) is safe for adults with severe autoimmune diseases like lupus, rheumatoid arthritis, or scleroderma that haven't improved with standard treatments. The main goal is to ch…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: PHASE1 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated May 17, 2026 00:43 UTC
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Engineered immune cells take aim at lupus in new trial
Disease control Not yet recruitingThis early-stage trial tests a new treatment called BCMA-CD19-IL-15 cCAR T cells for people with severe lupus that hasn't responded to standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and destroy faulty immune cells that cause lupus…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: PHASE1, PHASE2 • Sponsor: iCell Gene Therapeutics • Aim: Disease control
Last updated May 17, 2026 00:42 UTC
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New lupus injection enters human testing
Disease control Not yet recruitingThis study tests a new drug called HC022 in 32 people with lupus (SLE or CLE). The main goal is to see if it is safe and tolerable when given as multiple injections under the skin. Researchers will also measure how the drug moves through the body and whether it triggers an immune…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: PHASE1 • Sponsor: HC Biopharma Inc. • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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New lupus drug trial aims to tame the immune system
Disease control Not yet recruitingThis study tests a new medicine, SCTC21C, in about 159 adults with systemic lupus erythematosus (SLE), a chronic autoimmune disease. The goal is to see if the drug is safe and can help control lupus symptoms. Participants must be on stable standard treatments and have moderate to…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: PHASE1, PHASE2 • Sponsor: Sinocelltech Ltd. • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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New cell therapy trial offers hope for kids with tough autoimmune diseases
Disease control Not yet recruitingThis early-stage study will test a new cell therapy called YTS109 in 12 children aged 5 to 17 with severe autoimmune diseases like lupus and scleroderma that haven't responded to other treatments. The goal is to see if the therapy is safe and can help control the disease. Childre…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Phase: PHASE1 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Lupus blood markers under the microscope
Knowledge-focused Not yet recruitingThis study compares blood levels of two substances, MicroRNA-101-3p and Autotaxin, between 40 people with lupus and healthy volunteers. The goal is to see if these substances can serve as simple blood markers to track lupus activity. No treatment is given; the study only collects…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Sponsor: Eman Mohamed Shawky • Aim: Knowledge-focused
Last updated May 17, 2026 00:29 UTC
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700 lupus patients tracked from day one to unlock disease secrets
Knowledge-focused Not yet recruitingThis study will follow about 700 adults recently diagnosed with lupus across Europe for up to 5 years. Researchers want to see how many patients reach low disease activity or remission in the first year, and find biological markers in blood or urine that predict treatment respons…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Lupus mystery: atypical cases finally get a closer look
Knowledge-focused Not yet recruitingThis study aims to better understand lupus when it shows up in unusual ways, such as with rare symptoms, late in life, or without the typical ANA antibody. Researchers will compare 400 people with typical and atypical lupus to see how these differences affect disease activity, or…
Matched conditions: SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC