SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

This study tested an experimental drug called EG-501 for people with lupus who experience cognitive impairment, often called "brain fog." The trial involved 131 participants who received either the drug or a placebo for 14 weeks. The goal was to see if EG-501 could safely improve…

This study tested two experimental drugs, VAY736 and CFZ533, in 107 people with systemic lupus erythematosus (SLE). The goal was to see if these drugs could reduce disease activity and allow patients to lower their steroid use. The trial was completed and focused on safety, toler…

This study tested an 8-session online support program called WHEEL for people with lupus. The program, led by a health coach, helps participants set personal health goals and address symptoms like fatigue, pain, and brain fog that often aren't covered in regular doctor visits. 36…

This study created a registry to collect medical information from 868 patients with Anti-Phospholipid Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE). The goal was to better understand these autoimmune conditions. No treatments were tested; the focus was on gathering dat…

This study looked at the genes and immune systems of 271 children and adults with lupus, a chronic autoimmune disease. The goal was to find genetic mutations linked to lupus, especially in children or those with a family history. Researchers hope this will lead to a better unders…

This study looked at 124 people with lupus or mixed connective tissue disease to understand how their immune systems go wrong and how the diseases progress over time. Researchers measured immune cell responses and tracked symptoms to learn more about these long-term autoimmune co…

This study tested a patient navigator program for 75 minority adults with lupus. The program helped patients schedule appointments, arrange transportation, and find financial aid. The goal was to see if this support improves quality of life and medication adherence over 12 months…