SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

This study tested whether a drug called EG-501 could improve thinking and memory problems, often called 'brain fog,' in people with lupus. 131 adults with lupus and confirmed cognitive impairment were randomly assigned to receive either EG-501 or a placebo (inactive substance) fo…

This study tested two experimental drugs, VAY736 and CFZ533, in people with active lupus to see if they are safe and can help control the disease. Over 100 participants were randomly assigned to receive either one of the drugs or a placebo for 28 weeks, followed by a period where…

This study tested whether a patient navigator program could help minority patients with lupus get better care. The navigators helped with scheduling appointments, arranging transportation, understanding medications, and providing emotional support. Researchers wanted to see if th…

This study tested an 8-session online health coaching program designed to help people with lupus (SLE) better manage symptoms like fatigue, pain, and brain fog that heavily impact daily life. The program, called WHEEL, used group video sessions and one-on-one coaching to help 36 …

This study aimed to better understand the genetic and immune system causes of lupus, especially in children and families. Researchers analyzed blood samples from 271 participants with lupus to look for specific gene changes and measure immune cell activity. The goal was to connec…

This study created a registry to collect medical information from patients with anti-phospholipid syndrome (APS) and/or systemic lupus erythematosus (SLE). It enrolled 868 participants to gather data about their conditions and treatments. The goal was to better understand these a…

This study aimed to better understand how the immune system goes wrong in people with systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD). Researchers observed 124 participants with these conditions over time, collecting health information and blood samp…