New lupus injection enters first human tests

NCT ID NCT06144710

Completed Disease control Sponsor: Hangzhou Sumgen Biotech Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This early-stage trial tests a new drug called SG301, given as an injection under the skin every two weeks, for systemic lupus erythematosus (SLE). The study first gives a single dose to healthy volunteers to check safety, then gives multiple doses to people with lupus. The main goal is to see if the drug is safe and how the body processes it.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SG301 injection (a drug given under the skin every two weeks)
What this could lead to: If it works, this could point toward a new treatment option for systemic lupus erythematosus (SLE).
What could go wrong: This is a very early Phase 1 trial with only 48 participants, so it is primarily testing safety and dosing. It is too soon to know if the drug will actually help lupus symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Contacts and locations

Locations

First Affiliated Hospital of Xiamen University

Xiamen, Fujian, 361003, China
Huashan Hospital affiliated to Fudan University

Shanghai, Shanghai Municipality, 200040, China
Jiangxi Provincial People's Hospital

Nanchang, Jiangxi, 330006, China
Jining First People's Hospital

Jining, Shandong, 272002, China
Pingxiang People's Hospital

Pingxiang, Jiangxi, 337099, China
Shandong University Qilu Hospital

Jinan, Shandong, 250063, China
Shenzhen People's Hospital

Shenzhen, Guangdong, 518020, China
The First Affiliated Hospital of Bengbu Medical College

Bengbu, Anhui, 233000, China
The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, 350004, China
Zhejiang Provincial People's Hospital

Hangzhou, Zhejiang, 314408, China

More trials for these conditions

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