STAGE IVB PROSTATE CANCER AJCC V8

This study tested a combination of two drugs, apalutamide and abiraterone, along with prednisone, in men whose prostate cancer had spread and stopped responding to standard hormone therapy. The goal was to see if this combination could slow cancer growth. Only 7 men took part bef…

This study tested the drug erdafitinib in 11 men with advanced prostate cancer that had spread to the bones and stopped responding to hormone therapy. The goal was to see if erdafitinib could help control the cancer by blocking certain growth signals. Researchers also collected b…

This early-phase trial tested a new combination of two drugs—decitabine/cedazuridine and enzalutamide—in 8 men with advanced prostate cancer that had stopped responding to standard treatment. The goal was to find a safe dose and see if the combination could reverse drug resistanc…

This early-phase study tested whether adding the immunotherapy drug vudalimab (XmAb20717) to standard hormone therapy or chemotherapy could help men with prostate cancer that has spread. Only 4 men took part before the study was stopped. The main goals were to check safety and se…

This study tested a new imaging agent called 68Ga-PSMA-11 to see if it could give clearer pictures of where prostate cancer has spread in men with advanced, treatment-resistant disease. The goal was to help doctors better understand the location of tumors. The study was terminate…

This study tested a radioactive drug called Sn-117m-DTPA to see if it could reduce bone pain in men with prostate cancer that had spread to their bones and no longer responded to hormone therapy. Only one person enrolled before the study was stopped. The goal was to measure pain …

This study offered free genetic testing to nearly 800 men whose prostate cancer had spread. Researchers looked for inherited gene changes linked to cancer risk and asked participants about their feelings on testing. The goal was to learn if this approach works and to gather infor…