STAGE IVA LIP AND ORAL CAVITY CANCER AJCC V8
Clinical trials for STAGE IVA LIP AND ORAL CAVITY CANCER AJCC V8 explained in plain language.
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New drug combo aims to boost radiation for head and neck cancer
Disease control Recruiting nowThis early-phase trial is testing whether adding the experimental drug ipatasertib to standard chemotherapy and radiation can better control advanced head and neck cancer. About 46 adults with certain types of head and neck cancer will receive the combination to find the safest d…
Matched conditions: STAGE IVA LIP AND ORAL CAVITY CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 07:06 UTC
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Could a chemo drug boost radiation for head and neck cancer survivors?
Disease control Recruiting nowThis study compares radiation therapy alone versus radiation plus the chemotherapy drug cisplatin in people with stage III-IVA head and neck cancer who have already had surgery to remove their tumor. About 189 participants will be randomly assigned to one of the two treatments. T…
Matched conditions: STAGE IVA LIP AND ORAL CAVITY CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 17, 2026 07:06 UTC
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Could a Two-Drug punch before surgery beat head and neck cancer?
Disease control Recruiting nowThis study tests whether adding an experimental drug (CDX-1140) to a standard immunotherapy (cemiplimab) before surgery can shrink advanced head and neck cancers more than the immunotherapy alone. About 44 people with stage III-IV head and neck cancer will receive either the comb…
Matched conditions: STAGE IVA LIP AND ORAL CAVITY CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New combo therapy aims to boost survival in returning head and neck cancer
Disease control Recruiting nowThis study tests whether adding chemotherapy or a chemo-immunotherapy combination before standard salvage surgery helps people with a specific type of head and neck cancer that has come back or persisted. About 180 adults with PD-L1 positive cancer will be randomly assigned to on…
Matched conditions: STAGE IVA LIP AND ORAL CAVITY CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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New drug aims to ease painful mouth sores for head and neck cancer patients
Symptom relief Recruiting nowThis study tests whether adding BMX-001 to standard care can reduce severe mouth sores caused by chemoradiation in head and neck cancer patients. About 98 participants will receive either BMX-001 or a placebo alongside their usual treatment. The goal is to improve quality of life…
Matched conditions: STAGE IVA LIP AND ORAL CAVITY CANCER AJCC V8
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 17, 2026 07:07 UTC