New drug combo aims to boost chemoradiation for head and neck cancer
NCT ID NCT05172245
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 5 times
Summary
This early-phase study tests whether adding the experimental drug ipatasertib to standard chemotherapy and radiation is safe and effective for people with advanced head and neck cancer. Ipatasertib may help stop cancer cell growth. About 46 participants will receive the combination to find the best dose and check for side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atrium Health Cabarrus/LCI-Concord
ACTIVE_NOT_RECRUITINGConcord, North Carolina, 28025, United States
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Carolinas Medical Center/Levine Cancer Institute
ACTIVE_NOT_RECRUITINGCharlotte, North Carolina, 28203, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Email: •••••@•••••
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Montefiore Medical Center - Moses Campus
RECRUITINGThe Bronx, New York, 10467, United States
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Montefiore Medical Center-Einstein Campus
RECRUITINGThe Bronx, New York, 10461, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact Email: •••••@•••••
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Rutgers Cancer Institute of New Jersey
RECRUITINGNew Brunswick, New Jersey, 08903, United States
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Rutgers New Jersey Medical School
RECRUITINGNewark, New Jersey, 07101, United States
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University Health Network-Princess Margaret Hospital
SUSPENDEDToronto, Ontario, M5G 2M9, Canada
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University of Cincinnati Cancer Center-UC Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
Contact Email: •••••@•••••
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University of Cincinnati Cancer Center-West Chester
RECRUITINGWest Chester, Ohio, 45069, United States
Contact Email: •••••@•••••
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Kansas Clinical Research Center
RECRUITINGFairway, Kansas, 66205, United States
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University of Kansas Hospital-Westwood Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
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University of Kentucky/Markey Cancer Center
ACTIVE_NOT_RECRUITINGLexington, Kentucky, 40536, United States
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University of Maryland/Greenebaum Cancer Center
RECRUITINGBaltimore, Maryland, 21201, United States
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University of Virginia Cancer Center
SUSPENDEDCharlottesville, Virginia, 22908, United States
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VCU Massey Comprehensive Cancer Center
RECRUITINGRichmond, Virginia, 23298, United States
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Other studies related to the condition(s) this trial covers.
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