STAGE III RENAL CELL CANCER AJCC V8
Clinical trials for STAGE III RENAL CELL CANCER AJCC V8 explained in plain language.
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Major cancer trial aims to find best drug combo for advanced kidney cancer
Disease control OngoingThis large, late-stage trial is comparing two different drug combination strategies to control advanced kidney cancer that has spread. It involves over 1,100 patients with intermediate or high-risk disease. The study aims to see if adding a drug called cabozantinib to a standard …
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 20:11 UTC
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Targeted drug trial aims to halt growth of advanced tumors with genetic flaw
Disease control OngoingThis study is testing a drug called adavosertib in people with advanced solid tumors that have spread and have a specific genetic change called SETD2-deficiency. The goal is to see if the drug can shrink or stop the growth of these tumors by blocking enzymes the cancer cells need…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Gut bacteria boost: could a probiotic supercharge cancer treatment?
Disease control OngoingThis early-stage study is testing if adding a probiotic called CBM588 to standard cancer drugs (cabozantinib and nivolumab) can help patients with advanced kidney cancer. The probiotic aims to improve the mix of 'good' bacteria in the gut, which might help the body's immune syste…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Personalized immune cells tested to fight five tough cancers
Disease control TerminatedThis early-stage study aimed to test the safety and early effectiveness of a personalized cell therapy called STIL101. The therapy involved growing a patient's own cancer-fighting immune cells (T-cells) from a tumor sample in a lab and then infusing them back. It was designed for…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New drug combo tested for aggressive, rare kidney cancer
Disease control OngoingThis study is testing whether adding a new drug called ixazomib to two standard chemotherapy drugs works better for controlling an aggressive type of kidney cancer that has spread. It is for patients aged 12 and older whose cancer has progressed after other treatments and who hav…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Scientists test Triple-Threat drug combo against Tough-to-Treat cancers
Disease control OngoingThis early-stage study is testing the safety and best doses of a combination of cancer drugs for people with advanced cancers of the urinary system (like bladder and kidney cancer) that have spread. The trial combines a pill (cabozantinib) that aims to block tumor growth with one…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Berry boost for cancer fight? trial tests natural Add-On to immunotherapy
Disease control TerminatedThis early-stage study is testing if adding a natural berry supplement called camu camu makes standard immunotherapy drugs work better for people with advanced kidney cancer that has spread. The main goal is to check if the combination is safe and to find the right dose of camu c…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New combo therapy trial offers hope for HIV patients with advanced cancers
Disease control OngoingThis is a small, early-stage safety study testing a combination of two cancer drugs, nivolumab and cabozantinib, in people living with HIV who have advanced solid tumors. The main goal is to see if the two-drug combination is safe and tolerable for this specific patient group. Re…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug duo tested in fight against rare, aggressive kidney cancer
Disease control OngoingThis study is testing whether combining two cancer drugs works better than using just one to treat an aggressive form of kidney cancer that has spread or cannot be removed by surgery. The trial is enrolling patients of all ages, from children to adults. Researchers want to see if…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New hope for tough kidney cancers: Head-to-Head drug battle begins
Disease control OngoingThis study compares two different drug treatments for people with advanced kidney cancer that has spread and continued to grow despite previous immunotherapy. Researchers want to see whether a combination of two drugs (lenvatinib plus everolimus) works better than a single drug (…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New hope for shrinking tough kidney tumors before surgery
Disease control OngoingThis study is testing if taking the drug cabozantinib for 12 weeks before surgery can shrink advanced kidney tumors that have not spread. The goal is to see if this pre-surgery treatment helps control the cancer and makes surgery more effective. Researchers will measure tumor shr…
Matched conditions: STAGE III RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC